Poison Build Guide

Poison is one of the most discussed mechanics in Dicero because it can feel weak early and powerful later. This build route is for players who want sustained damage over time instead of immediate burst.

What is Poison?

Poison deals damage over time (DOT). It doesn’t require you to roll the dice actively — it just ticks away.

That makes the route strongest when the fight lasts long enough for poison to stack. If enemies die quickly, or if the stage demands immediate burst, the same setup can feel slow.

Community Debate

There’s been significant community discussion about Poison:

Arguments FOR Poison

“Poison stacks for each dice, really strong once you get it going” — Community member

“Acorn Miasma + Does Not Enter Play has crazy synergy” — Community member

Arguments AGAINST

“Ramp-up takes too long for short fights” — Community member

“Can’t remove poison from your pool once it’s there” — Community member

Key Upgrades

If running Poison, prioritize:

1. Does Not Enter Play - Keeps poison dice in the pool
2. Poison Stacks - Increases DOT damage
3. Miasma Synergies - Community has found some powerful combos

Works Best For

• Long boss fights where damage over time has room to stack
• Runs that already offer poison-supporting upgrades
• Players who can survive while passive damage builds up

Watch Out For

• Short encounters where ramp-up time is wasted
• Stages that require fast burst instead of sustained damage
• Taking poison too early without enough supporting upgrades

Community Verdict

• ✅ Good for: Long boss fights where you can stack damage
• ❌ Avoid for: Short encounters or time-limited stages
• ⚠️ Warning: Can’t be removed from dice pool once selected

Next Step

If you are not sure whether to take Poison at all, read the Poison Guide first. Use this build page only after you decide the current run can support a slower, stacking route.